Periodontics · single question

Which cells are most associated with chronic (established) periodontitis lesions?

  1. Lymphocytes
  2. Macrophages
  3. Neutrophils
  4. Plasma cells
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Correct answer: D. Plasma cells

Per the classic Page & Schroeder histologic staging of periodontal disease, the advanced/established chronic lesion is characterized by a predominance of plasma cells (and B-lymphocytes), reflecting a mature, chronic humoral immune response — distinct from the neutrophil-dominated early/acute lesion.

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