Which cell type predominates in suppuration (pus formation)?

Correct answer: D. Neutrophils

• A. Macrophages dominate chronic and granulomatous inflammation, and clean up after the acute phase.
• B. Lymphocytes characterize chronic inflammation and the early established gingival lesion (T cells in the early lesion, B cells and plasma cells later).
• C. Plasma cells dominate CHRONIC inflammation and are the hallmark cell of established periodontitis lesions, producing antibody.
• D. CORRECT. Pus is composed principally of degenerating NEUTROPHILS (polymorphonuclear leukocytes) together with liquefied necrotic tissue, bacteria, and edema fluid. Neutrophils are the first responders of ACUTE inflammation, arriving within hours; their lysosomal enzymes produce the liquefactive necrosis that creates an abscess cavity.

Note: Timeline: neutrophils (hours, acute) → macrophages (days) → lymphocytes and plasma cells (chronic).