Pathology · single question
Which cancer involves multiple punched-out radiolucencies in a young child (age 2u20134)?
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Correct answer: B. Langerhans cell histiocytosis
Multiple punched-out radiolucencies in a young child are characteristic of Langerhans cell histiocytosis (peak incidence age 2u20134). Multiple myeloma causes similar radiographs but is a disease of elderly patients (average age 70). Age is the critical differentiator.