Pharmacology · single question
Which agent is LEAST likely to cross-react (the safe EXCEPTION)?
Patient reports allergy to an AMIDE local anesthetic (lidocaine).
Show answer and explanation
Correct answer: A. Tetracaine
Esters (tetracaine) do not cross-react with amides (lidocaine, prilocaine, mepivacaine).
- A. Correct — the exception. Tetracaine is an ESTER; esters and amides do not cross-react, so it would not trigger an amide allergy.
- B. An amide — same class as lidocaine, potential cross-reactivity.
- C. An amide — potential cross-reactivity with an amide allergy.