Pathology · single question

What is the standard first-line treatment for pemphigus vulgaris?

  1. Antifungal therapy
  2. Systemic corticosteroids (often with adjunctive immunosuppressants for steroid-sparing effect)
  3. Antiviral therapy
  4. Antibiotic therapy
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Correct answer: B. Systemic corticosteroids (often with adjunctive immunosuppressants for steroid-sparing effect)

Pemphigus vulgaris is a potentially life-threatening autoimmune blistering disease requiring systemic corticosteroids as first-line therapy, frequently combined with steroid-sparing immunosuppressants (e.g., rituximab, azathioprine, mycophenolate) for long-term control.

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