Pathology · patient case question

All of the following belong in the differential diagnosis of a submucosal buccal mucosa nodule EXCEPT:

Patient case: Two white lesions and a brown one

demo: Three patients seen in one session

chief: Assorted mucosal lesions identified during routine examination.

history: The first is a 24-year-old with a lifelong asymptomatic finding whose brother has the same appearance. The second is a 41-year-old with bilateral buccal findings. The third is a 52-year-old who has chewed betel nut for twenty years.

meds: None relevant.

findings: Patient one has a diffuse, thick, spongy, folded white lesion of the floor of the mouth and buccal mucosa that does not rub off. Patient two has a diffuse blue-grey filmy opacity of both buccal mucosae that fades when the cheek is stretched. Patient three has brownish-red clustered staining of the buccal mucosa near teeth 18 and 19 with a marbled pallor and reduced mouth opening.

  1. Lipoma
  2. Traumatic fibroma
  3. Schwannoma
  4. Nicotinic stomatitis
Show answer and explanation

Correct answer: D. Nicotinic stomatitis

  • A. A lipoma presents as a soft, yellowish, sometimes fluctuant submucosal mass and is a legitimate consideration.
  • B. A traumatic fibroma is the single most common submucosal nodule of the buccal mucosa, arising along the occlusal line from cheek biting.
  • C. A schwannoma is a benign nerve sheath tumour that presents as a slow-growing, painless, firm submucosal nodule and belongs in the differential.
  • D. Correct, and this is the exception. Nicotinic stomatitis is a diffuse surface change of the hard palate, a grey-white keratosis with red punctate duct openings. It is neither a nodule nor a buccal mucosa lesion, so it does not belong in this differential.

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