Pharmacology · single question
What is the side effect of isoniazid (INH) most relevant to dentistry?
Show answer and explanation
Correct answer: A. Hepatotoxicity
- A. Correct. HEPATOTOXICITY is the most clinically significant side effect of isoniazid (INH). INH can cause drug-induced hepatitis, ranging from asymptomatic transaminase elevation to fulminant liver failure. This is relevant dentally because liver disease affects drug metabolism and bleeding — dental patients on INH should be monitored for hepatic impairment.
- B. Incorrect. Isoniazid does not have significant direct cardiotoxicity.
- C. Incorrect. Ototoxicity (hearing damage) is associated with aminoglycosides (streptomycin), not isoniazid.
- D. Incorrect. Nephrotoxicity is not a major side effect of isoniazid.