Pharmacology · single question
What is the primary mechanism of action of nitrous oxide as an anesthetic agent?
Show answer and explanation
Correct answer: A. NMDA receptor inhibition
Nitrous oxide (N2O) primarily acts as an NMDA (N-methyl-D-aspartate) glutamate RECEPTOR ANTAGONIST. It blocks these excitatory receptors, producing its analgesic and anesthetic effects. It also has some opioid receptor activity (weak — D partially true but NOT primary). Benzodiazepines and barbiturates work via GABA (B wrong). Local anesthetics block sodium channels (C wrong). The primary MOA is NMDA receptor inhibition. A is correct.