Micro & Immunology · single question
What is the primary function of IgA in saliva?
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Correct answer: A. Antimicrobial defense (neutralizing pathogens)
Secretory IgA (sIgA) is the predominant immunoglobulin in saliva. Its primary function is antimicrobial — it binds pathogens (bacteria, viruses) to prevent adherence to mucosal surfaces (immune exclusion). It does not cause cell lysis (that's complement/IgM). It doesn't neutralize acids or promote remineralization (fluoride/saliva minerals do that).
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