Pharmacology · single question

What is the mechanism of action of ibuprofen?

  1. Irreversible cyclooxygenase inhibitor
  2. Non-selective cyclooxygenase inhibitor
  3. 5-Lipoxygenase inhibitor
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Correct answer: B. Non-selective cyclooxygenase inhibitor

Ibuprofen = reversible, non-selective COX inhibitor.
  • A. That is aspirin (irreversible). Ibuprofen is reversible.
  • B. Correct. Ibuprofen reversibly and non-selectively inhibits COX-1 and COX-2.
  • C. That is zileuton, not ibuprofen.

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