Pharmacology · single question
What is the mechanism of action of apixaban (and rivaroxaban)?
Show answer and explanation
Correct answer: A. Direct factor Xa inhibitor
- A. Correct. Apixaban and rivaroxaban selectively inhibit factor Xa, blocking conversion of prothrombin to thrombin.
- B. Warfarin is the vitamin K antagonist; apixaban is not.
- C. Dabigatran is the direct thrombin (IIa) inhibitor.
- D. Aspirin is the COX-inhibiting antiplatelet; different mechanism.