Pharmacology · single question
What is the mechanism of action of adalimumab (Humira)?
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Correct answer: C. TNF-alpha inhibitor (monoclonal antibody)
- A. That describes tocilizumab.
- B. That describes rituximab.
- C. Correct. Adalimumab is a fully human monoclonal antibody that binds and neutralizes TNF-alpha. Dental relevance: these patients are immunosuppressed with increased infection and delayed-healing risk.
- D. That describes cyclosporine/tacrolimus — cyclosporine is the one associated with gingival overgrowth.
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