Biostatistics & Research · single question

What is the highest level of evidence in evidence-based dentistry?

  1. Randomized controlled trial (RCT)
  2. Case series
  3. Cohort study
  4. Systematic review and meta-analysis
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Correct answer: D. Systematic review and meta-analysis

Systematic reviews and meta-analyses represent the highest level of evidence in the evidence-based dentistry hierarchy. They synthesize data from multiple well-designed studies using rigorous, predefined methodology to provide the most reliable overall estimate of an intervention's effectiveness or a risk factor's importance. A meta-analysis uses statistical methods to pool results from multiple RCTs or other studies. The Cochrane Collaboration produces many systematic reviews relevant to dentistry. Individual RCTs are below systematic reviews in the hierarchy. Note: this question is a duplicate of question 39 (Q75 in the original batch) and question 78 (Q133) within the same batch, reflecting repeated testing of this concept.

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