Pathology · single question

What is the BEST pharmacological treatment for lateral pterygoid myospasm causing jaw deviation?

  1. Ibuprofen
  2. Cyclobenzaprine (muscle relaxant)
  3. Amoxicillin
  4. Clonazepam
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Correct answer: B. Cyclobenzaprine (muscle relaxant)

Cyclobenzaprine is a centrally acting muscle relaxant — first-line pharmacotherapy for acute myospasm.
  • A. Ibuprofen addresses inflammation and pain but does not specifically relax spastic muscle — it is a useful adjunct but not primary treatment.
  • B. CORRECT. Cyclobenzaprine (Flexeril) is a centrally acting muscle relaxant structurally similar to TCAs. It is first-line pharmacotherapy for acute muscle spasm including lateral pterygoid myospasm causing TMD.
  • C. Amoxicillin is an antibiotic with no role in treating muscle spasm.
  • D. Clonazepam can be used for bruxism and some muscle conditions but cyclobenzaprine is the more specific choice for myospasm.

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