Medical Emergencies · single question

What antibiotic prophylaxis does a patient with multiple myeloma require before dental treatment?

  1. Clindamycin 600 mg
  2. Azithromycin 500 mg
  3. Amoxicillin 2 g
  4. None — multiple myeloma is not an indication for prophylaxis
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Correct answer: D. None — multiple myeloma is not an indication for prophylaxis

  • A. Clindamycin is an alternative regimen for a valid indication — none exists here.
  • B. Azithromycin is likewise an alternative for penicillin-allergic patients with a valid indication.
  • C. Amoxicillin prophylaxis is reserved for specific cardiac conditions and select prosthetic joint scenarios.
  • D. Correct. Multiple myeloma itself is not an AHA prophylaxis category. The real dental concerns are MRONJ risk from bisphosphonate therapy, bleeding from thrombocytopenia, and infection risk from chemotherapy-induced neutropenia — which may prompt physician consultation rather than routine prophylaxis.

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