Physiology & Biochemistry · single question
The sickle cell anemia mutation is classified as:
Show answer and explanation
Correct answer: C. Missense
- A. INCORRECT. A sense (silent) mutation would not change the amino acid.
- B. INCORRECT. A nonsense mutation creates a premature stop codon.
- C. CORRECT. A single base change substitutes valine for glutamic acid in beta-globin, a missense mutation.
- D. INCORRECT. A frameshift results from insertions or deletions, not a single substitution.
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