Physiology & Biochemistry · single question

A decrease in CO₂ levels in the blood (hypocapnia) will lead to which of the following?

  1. Decreased respiratory rate
  2. Increased tidal volume
  3. Decreased oxygen demand
  4. Peripheral vasoconstriction
Show answer and explanation

Correct answer: A. Decreased respiratory rate

CO₂ is the primary driver of respiration. LOW CO₂ (hypocapnia) decreases the respiratory drive — the body breathes less because CO₂ is already low.
  • A. CORRECT. Decreased CO₂ (hypocapnia) decreases the respiratory drive — brainstem chemoreceptors detect low CO₂ and reduce respiratory rate. This is why hyperventilation (lowering CO₂) causes dizziness and eventually apnea.
  • B. Increased tidal volume occurs in response to HIGH CO₂ (hypercapnia), not low CO₂. Low CO₂ suppresses respiratory drive.
  • C. Oxygen demand relates to metabolic activity, not directly to CO₂ levels in this context.
  • D. Hypocapnia does cause vasoconstriction (CO₂ is a vasodilator), but decreased respiratory rate is the primary answer being tested here.

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