Pharmacology · single question

The patient takes lisinopril. Which best describes the mechanism of this antihypertensive?

  1. Inhibits calcium influx in vascular smooth muscle
  2. Blocks angiotensin II receptors
  3. Inhibits the angiotensin-converting enzyme (ACE)
  4. Increases norepinephrine release
Show answer and explanation

Correct answer: C. Inhibits the angiotensin-converting enzyme (ACE)

  • A. Calcium-channel blockers act on calcium influx; lisinopril is not one.
  • B. ARBs block AT1 receptors; lisinopril is not an ARB.
  • C. Correct. Lisinopril is an ACE inhibitor, reducing angiotensin II formation (and is associated with a dry cough/angioedema).
  • D. Lisinopril does not increase norepinephrine release.

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