Medical Emergencies · patient case question
The concentration 1:1000 corresponds to which amount of epinephrine per milliliter?
Patient case: Medical Emergency in the Operatory
demo: 34-year-old female
chief: Composite restoration on tooth #3 under rubber dam isolation.
history: Asthma, well controlled. No known drug allergies. Latex sensitivity not previously documented.
meds: Albuterol inhaler as needed
findings: Ten minutes after rubber dam placement the patient develops audible wheezing, swelling of the lips and periorbital tissue, and urticaria over the neck.
Show answer and explanation
Correct answer: A. 1 mg/mL
- A. Correct. A 1:1000 dilution is 1 gram in 1000 mL, which is 1 mg per mL — the intramuscular anaphylaxis concentration.
- B. 0.1 mg/mL is 1:10,000, the intravenous concentration used in cardiac arrest.
- C. 10 mg/mL would be 1:100, which is not a clinical preparation for this use.
- D. 0.01 mg/mL is 1:100,000, the concentration of epinephrine in local anesthetic cartridges.
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