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Pharmacology · single question

Terazosin (an alpha-1 blocker used for hypertension/BPH) is LEAST likely to be associated with which of the following?

  1. Palpitations
  2. Bleeding/coagulopathy
  3. Nasal congestion
  4. Dizziness and orthostatic hypotension
Show answer and explanation

Correct answer: B. Bleeding/coagulopathy

Terazosin is an alpha-1 adrenergic receptor blocker. Its side effects include orthostatic hypotension (especially first-dose), dizziness, nasal congestion (due to vasodilation of nasal mucosa), and palpitations. Bleeding or coagulopathy is NOT a known side effect of alpha-1 blockers. Dental relevance: terazosin patients may experience orthostatic hypotension when rising quickly from the dental chair.
  • A. ❌ Reflex tachycardia and palpitations can occur with alpha-1 blockers due to baroreceptor response to vasodilation.
  • B. ✅ CORRECT – Bleeding/coagulopathy is NOT associated with terazosin. It does not affect platelet function or coagulation.
  • C. ❌ Nasal congestion is a recognized side effect from vasodilation of nasal vessels.
  • D. ❌ Orthostatic hypotension and dizziness are the most common side effects of alpha-1 blockers.

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