T-helper (CD4+) cells release interleukin-2 (IL-2) to perform which function during infection?

IL-2 from CD4+ helper T cells is a T-cell growth factor that drives proliferation and activation of cytotoxic CD8+ T cells (and other lymphocytes), coordinating cell-mediated immunity.Other options: Direct killing is the role of CD8+ cells (after activation); antibody production is by plasma cells (B-lineage); phagocytosis is by macrophages/neutrophils.Key exam takeaway: CD4+ T cells coordinate immunity; IL-2 expands cytotoxic CD8+ T cells. HIV destroys CD4+ cells, causing immunodeficiency.