Pathology · single question
Secondary syphilis is characterized by:
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Correct answer: D. Maculopapular rash
- A. Cardiovascular syphilis (aortitis, aortic aneurysm) is a manifestation of TERTIARY syphilis — not secondary.
- B. Gumma (granulomatous nodule that can destroy bone and soft tissue) is a feature of TERTIARY syphilis — not secondary.
- C. Chancre (painless indurated ulcer) is the hallmark of PRIMARY syphilis — it resolves spontaneously before secondary syphilis manifests.
- D. Secondary syphilis classically presents as a widespread MACULOPAPULAR RASH, characteristically involving the PALMS OF THE HANDS and SOLES OF THE FEET — a pathognomonic finding. Other features: condyloma lata, mucous patches, split papules (oral lesions), and generalized lymphadenopathy. RPR and VDRL are positive.