Pathology · single question

Same patient presents with decreased salivary flow and decreased tear secretion. Most likely diagnosis?

  1. Sjögren syndrome
  2. Lupus erythematosus
  3. Rheumatoid arthritis
  4. Sarcoidosis
Show answer and explanation

Correct answer: A. Sjögren syndrome

  • A. Correct. The sicca complex — dry mouth (xerostomia) plus dry eyes (keratoconjunctivitis sicca) — is the defining presentation of Sjögren syndrome.
  • B. Lupus is a multisystem autoimmune disease but does not classically present with the primary sicca complex.
  • C. Rheumatoid arthritis can coexist with secondary Sjögren, but RA itself is a joint disease, not the cause of the dryness.
  • D. Sarcoidosis can cause gland involvement but is not the classic dry-eyes/dry-mouth diagnosis.

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