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Pathology · single question

Kaposi Sarcoma is a vascular tumor classically associated with which virus and appears clinically as:

  1. Purple-red macules/patches/nodules on skin or mucosa, associated with HHV-8 and HIV/AIDS
  2. White plaques on the tongue associated with EBV in immunocompromised patients
  3. Ulcerated lesions with rolled borders associated with HPV-16
  4. Raised yellow plaques on palatal mucosa associated with CMV
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Correct answer: A. Purple-red macules/patches/nodules on skin or mucosa, associated with HHV-8 and HIV/AIDS

Kaposi Sarcoma presents as purple-red to brown macules, patches, plaques, or nodules on skin or oral mucosa. It is caused by Human Herpesvirus 8 (HHV-8) and is strongly associated with HIV/AIDS (especially CD4 counts <200). In the oral cavity, it most commonly appears on the hard palate or gingiva. It is a vascular neoplasm — the color reflects blood vessel proliferation.

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