Pathology · single question

Same case (Type IV reaction, 4 weeks later, target lesions). What is the specific type of lesion?

  1. Epidermolysis bullosa
  2. Stevens-Johnson syndrome
  3. Erythema multiforme
  4. Bullous pemphigoid
Show answer and explanation

Correct answer: C. Erythema multiforme

  • A. ❌ Epidermolysis bullosa is a genetic blistering disorder.
  • B. ❌ Stevens-Johnson syndrome is a severe mucocutaneous reaction with extensive epidermal detachment — more severe than classic EM.
  • C. ✅ Correct. Target lesions (concentric ring — red center, pale ring, red outer ring) are pathognomonic of Erythema multiforme, a Type IV hypersensitivity reaction often triggered by drugs or infections.
  • D. ❌ Bullous pemphigoid shows tense bullae in elderly patients, not target lesions.

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