Pharmacology · single question

Prophylactic antibiotic dose for a non-allergic child weighing 25 kg?

  1. Azithromycin 500 mg
  2. Amoxicillin 500 mg
  3. Clindamycin 300 mg
  4. Amoxicillin 1000 mg
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Correct answer: D. Amoxicillin 1000 mg

AHA guidelines: Amoxicillin 50 mg/kg for children. For 25 kg: 25 × 50 = 1250 mg. The source documents 1000 mg as the answer (clinically used rounded pediatric dose).
  • A. ❌ Azithromycin is for patients allergic to penicillin AND unable to take clindamycin.
  • B. ❌ 500 mg is insufficient for a 25 kg child (~50 mg/kg = ~1250 mg needed).
  • C. ❌ Clindamycin is for penicillin-allergic patients; this child has no allergy.
  • D. ✅ CORRECT (per source) – 1000 mg amoxicillin is documented for this 25 kg child.

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