Pathology · single question
Patients with Peutz-Jeghers syndrome are at highest risk for developing which cancer?
Show answer and explanation
Correct answer: C. Gastrointestinal cancer (colorectal/small bowel)
Peutz-Jeghers = autosomal dominant: GI hamartomatous polyps + mucocutaneous melanin pigmentation (lips, oral mucosa). Elevated lifetime risk of GI cancers (small bowel, colorectal, gastric) + pancreatic, breast, gynecologic.