Micro & Immunology · single question

Oral lichen planus is classified as which type of hypersensitivity reaction?

  1. Type I
  2. Type II
  3. Type III
  4. Type IV
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Correct answer: D. Type IV

  • A. Type I is IgE-mediated immediate allergy.
  • B. Type II is antibody-mediated cytotoxicity.
  • C. Type III is immune-complex mediated.
  • D. Correct. Lichen planus is a Type IV (delayed, T-cell-mediated) reaction in which T lymphocytes attack basal keratinocytes; clinically shows Wickham striae, histologically Civatte bodies; treated with topical corticosteroids (e.g., clobetasol).

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