Micro & Immunology · single question

Secondary syphilis is characterized by:

  1. Maculopapular rash (including palms and soles)
  2. Gumma formation
  3. Painless chancre
  4. Neurosyphilis
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Correct answer: A. Maculopapular rash (including palms and soles)

✓ A) Maculopapular rash is correct.
Secondary syphilis (4–10 weeks after primary) features a generalized maculopapular rash classically involving the palms and soles — this is pathognomonic. Also seen: condylomata lata, mucous patches (highly infectious oral lesions), lymphadenopathy, fever. Primary syphilis = chancre. Tertiary syphilis = gumma, cardiovascular, neurosyphilis. Oral mucous patches in secondary syphilis require universal precautions.

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