Physiology & Biochemistry · single question
Oligodendroglioma is best classified as which of the following types of disorder?
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Correct answer: A. A primary brain tumor of CNS glial cells
- A. CORRECT. Oligodendroglioma is a primary CNS tumor arising from oligodendrocytes (the myelin-producing glial cells of the brain). It is characterized histologically by 'fried egg' cells and calcifications. It is a neoplasm, not an autoimmune or infectious disease.
- B. Metabolic storage diseases (e.g., Gaucher, Tay-Sachs) involve enzyme deficiencies causing substrate accumulation; oligodendroglioma is not in this category.
- C. Autoimmune demyelinating diseases include multiple sclerosis and ADEM. Oligodendroglioma is a neoplasm, not an autoimmune condition.
- D. Viral encephalitis involves infection of brain parenchyma by viruses; oligodendroglioma has no infectious etiology.
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