Physiology & Biochemistry · single question

Multiple Sclerosis (MS) is a demyelinating disease involving oligodendrocytes. How is it classified?

  1. Reactive (inflammatory response to infection)
  2. Developmental (abnormal development of the nervous system)
  3. Autoimmune (immune-mediated attack on myelin/oligodendrocytes)
  4. Hereditary (single gene mutation)
Show answer and explanation

Correct answer: C. Autoimmune (immune-mediated attack on myelin/oligodendrocytes)

Multiple Sclerosis (MS) is classified as an autoimmune disease. The immune system attacks the myelin sheath produced by oligodendrocytes in the CNS, causing demyelinating plaques. This leads to impaired nerve conduction and the characteristic relapsing-remitting or progressive neurological symptoms. While genetic susceptibility exists, it is not a single-gene hereditary condition — it is the autoimmune attack that defines its pathophysiology.

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