Pathology · single question
Multiple myeloma is a malignancy involving which cell type?
Show answer and explanation
Correct answer: D. Plasma cells (malignant monoclonal proliferation)
- A. Reed-Sternberg cells are characteristic of Hodgkin's lymphoma — not multiple myeloma.
- B. T lymphocyte malignancies include T-cell lymphomas and T-cell leukemias — not multiple myeloma.
- C. Neutrophil malignancies are not described as multiple myeloma.
- D. Correct. Multiple myeloma is a malignant dyscrasia of plasma cells — specifically uncontrolled proliferation of monoclonal plasma cells in the bone marrow. These cells produce excessive monoclonal immunoglobulin (M protein) and cause bone destruction, immune suppression, and renal damage.