Pathology · single question

A description in the patient's chart mentions Civatte bodies. What medication should be given to this patient?

  1. Clobetasol
  2. Clotrimazole
  3. Amoxicillin
  4. Acyclovir
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Correct answer: A. Clobetasol

Civatte bodies (apoptotic basal keratinocytes) are a classic histologic finding in lichen planus. The standard first-line treatment for symptomatic oral lichen planus is a potent topical corticosteroid such as clobetasol — not an antifungal (clotrimazole), antibiotic (amoxicillin), or antiviral (acyclovir), none of which target the immune-mediated inflammatory process of lichen planus.

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