Pathology · single question
A description in the patient's chart mentions Civatte bodies. What medication should be given to this patient?
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Correct answer: A. Clobetasol
Civatte bodies (apoptotic basal keratinocytes) are a classic histologic finding in lichen planus. The standard first-line treatment for symptomatic oral lichen planus is a potent topical corticosteroid such as clobetasol — not an antifungal (clotrimazole), antibiotic (amoxicillin), or antiviral (acyclovir), none of which target the immune-mediated inflammatory process of lichen planus.