Pathology · single question
Most likely diagnosis?
≈12–17-yr-old girl, bilateral swelling, ~half normal stature, elevated TSH with low T3 and T4. (NOT cherubism.)
Show answer and explanation
Correct answer: A. Cretinism (juvenile/congenital hypothyroidism)
The thyroid profile (↑TSH, ↓T3/T4) and growth failure point to hypothyroidism (cretinism), not a jaw lesion.
- A. Correct. High TSH + low T3/T4 + severe growth retardation = hypothyroidism; in a child this is cretinism.
- B. Cherubism is a genetic fibro-osseous jaw lesion with no thyroid/stature abnormality — explicitly excluded here.