Pathology · single question

Microscopic examination of a bone marrow biopsy in this patient would reveal predominantly:

  1. Neutrophils
  2. Lymphoblasts
  3. Plasma cells
  4. Eosinophils
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Correct answer: C. Plasma cells

Multiple myeloma is a clonal proliferation of plasma cells producing monoclonal immunoglobulin. Classic tetrad (CRAB): hyperCalcemia, Renal failure, Anemia, Bone lesions (punched-out lytic lesions, including in the jaw and skull). Bence-Jones protein (light chains) in urine is characteristic.

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