Oral Surgery · single question
Medication-related osteonecrosis of the jaw (MRONJ) can be caused by which class of medications, beyond bisphosphonates?
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Correct answer: A. Anti-angiogenic agents
Anti-angiogenic medications (such as bevacizumab and certain tyrosine kinase inhibitors used in cancer treatment) are recognized, in addition to bisphosphonates and denosumab (a RANKL inhibitor), as a cause of medication-related osteonecrosis of the jaw, given their effects on bone vascularity and remodeling.