Pharmacology · single question
Mechanism of action of Humira (adalimumab):
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Correct answer: A. TNF-alpha inhibitor (monoclonal antibody against TNF-α)
- A. Correct. Adalimumab is a monoclonal antibody that binds and inhibits TNF-α, reducing inflammation in conditions like rheumatoid arthritis, Crohn's disease, and psoriasis.
- B. IL-2 receptor blockers (e.g., basiliximab) are different biologics, used mainly in transplant rejection prophylaxis.
- C. RANKL inhibition describes denosumab's mechanism, not adalimumab's.
- D. Calcineurin inhibitors (e.g., cyclosporine, tacrolimus) work through a completely different immunosuppressive pathway.