Kaposi's sarcoma is caused by which virus?

Kaposi's sarcoma is caused by Human Herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV). It is an AIDS-defining malignancy most commonly seen in severely immunocompromised HIV-positive patients (CD4 count <200 cells/μL). Oral Kaposi's sarcoma typically presents as red, purple, or brown macules, plaques, or nodules on the hard palate and gingiva. It may be the first manifestation of HIV/AIDS. Classic (non-HIV) Kaposi's sarcoma occurs in elderly men of Mediterranean or Eastern European Jewish descent and is less aggressive.