Medical Emergencies · single question

Janeway lesions (on hands and feet) are associated with which systemic condition?

  1. Pulmonary embolism
  2. Infective endocarditis
  3. Systemic lupus erythematosus
  4. Rheumatoid arthritis
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Correct answer: B. Infective endocarditis

✓ B) Infective endocarditis is correct.
Janeway lesions are small, painless, hemorrhagic macules on the palms and soles — embolic/septic phenomena from infective endocarditis (IE). Other IE signs: Osler's nodes (painful, on fingers/toes), Roth spots (retinal hemorrhages), splinter hemorrhages (fingernails), and new heart murmur. Dental significance: patients with previous IE require antibiotic prophylaxis for certain dental procedures. Janeway lesions are non-tender (vs. Osler's nodes which ARE tender).

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