Medical Emergencies · single question
Janeway lesions found on the palms and soles are a classic sign of which condition?
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Correct answer: B. Infective endocarditis
- A. Pulmonary embolism presents with sudden dyspnea, pleuritic chest pain, and hypoxia — it does not cause Janeway lesions.
- B. Janeway lesions are painless, flat, hemorrhagic macules on the palms and soles, caused by septic emboli. They are a MAJOR peripheral manifestation of infective endocarditis (IE). ✓ Compare with Osler's nodes (painful, on fingertips) also seen in IE.
- C. SLE causes a butterfly rash, serositis, and renal disease — Janeway lesions are not characteristic of SLE.
- D. Rheumatic fever causes Osler's nodes (painful nodules), erythema marginatum, and Sydenham's chorea — not Janeway lesions.
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