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Pathology · single question

In the management of Pemphigus Vulgaris, what should NOT be used?

  1. Air abrasive jet (air polisher)
  2. High-potency topical corticosteroids
  3. Perilesional biopsy technique
  4. Systemic corticosteroids
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Correct answer: A. Air abrasive jet (air polisher)

  • A. ✅ Correct. Air abrasive/polishing jets should NOT be used in PV. The high-pressure air-water-abrasive stream traumatizes the fragile mucosa, triggers Nikolsky's sign equivalent, and induces new blister formation in the acantholytic epithelium.
  • B. ❌ High-potency topical corticosteroids ARE used for oral PV lesion management.
  • C. ❌ Perilesional biopsy (sampling from the edge of the lesion in apparently normal tissue) IS the recommended technique for PV.
  • D. ❌ Systemic corticosteroids ARE the mainstay of PV treatment.

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