Pharmacology · single question
In a patient with liver cirrhosis requiring dental antibiotics, which antibiotic is preferred?
Show answer and explanation
Correct answer: A. Penicillin VK
✓ A) Penicillin VK is correct.
Penicillin VK is primarily renally excreted and does not require significant hepatic metabolism, making it safe in liver disease. Metronidazole, clindamycin, erythromycin, and tetracyclines are substantially hepatically metabolized and should be used cautiously or avoided in significant liver disease. Penicillin remains the drug of choice for dental infections in patients with hepatic impairment.
Penicillin VK is primarily renally excreted and does not require significant hepatic metabolism, making it safe in liver disease. Metronidazole, clindamycin, erythromycin, and tetracyclines are substantially hepatically metabolized and should be used cautiously or avoided in significant liver disease. Penicillin remains the drug of choice for dental infections in patients with hepatic impairment.