Pathology · single question
HPV type 16 is most strongly associated with which of the following?
Show answer and explanation
Correct answer: C. Oropharyngeal squamous cell carcinoma
HPV-16 is a high-risk oncogenic type most strongly associated with oropharyngeal SCC, particularly tonsillar and base-of-tongue cancers. It is the most aggressive HPV type relevant to dentistry.
- A. Recurrent respiratory papillomatosis is caused by low-risk HPV types 6 and 11.
- B. Focal epithelial hyperplasia (Heck disease) is caused by HPV types 13 and 32.
- C. CORRECT. HPV-16 = oropharyngeal squamous cell carcinoma. Most important high-risk HPV type for dentists.
- D. Condyloma acuminatum is caused by low-risk HPV types 6 and 11.