Pathology · single question
HIV-positive patient: white, corrugated, non-removable lesion on LATERAL border of tongue. Most likely diagnosis?
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Correct answer: C. Oral hairy leukoplakia (OHL)
OHL (EBV/HHV-4): white corrugated 'hairy' folds on LATERAL borders of tongue in immunocompromised patients. CANNOT be wiped off. Classic HIV-associated lesion. Geographic tongue = erythematous patches with white borders that migrate — NOT characteristically HIV-associated.