Pathology · single question

A patient with pemphigus vulgaris reports sensitivity to spicy foods and shows buccal mucosal erythema. This finding indicates:

  1. Active mucosal (oral) involvement of the disease
  2. Complete resolution of the disease
  3. A purely cutaneous (skin-only) flare
  4. An allergic contact reaction unrelated to pemphigus
Show answer and explanation

Correct answer: A. Active mucosal (oral) involvement of the disease

  • A. Correct. Oral mucosal lesions are often the first and most persistent sign of pemphigus vulgaris; spicy-food sensitivity and erythema reflect active mucosal disease.
  • B. Incorrect. Symptomatic erythema indicates active disease, not resolution.
  • C. Incorrect. The findings are intraoral (mucosal), by definition not skin-only.
  • D. Incorrect. In a known pemphigus patient, mucosal erythema is most consistent with the disease itself rather than a separate contact allergy.

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