Pathology · single question

Historically, what was the first AIDS-defining opportunistic infection associated with HIV?

  1. Pneumocystis jirovecii pneumonia
  2. Oral candidiasis
  3. Herpes zoster
  4. Tuberculosis
Show answer and explanation

Correct answer: A. Pneumocystis jirovecii pneumonia

  • A. Correct – Pneumocystis (PCP) pneumonia was the hallmark opportunistic infection that first defined the AIDS epidemic.
  • B. Incorrect – common and an early sign, but PCP is the classic AIDS-defining infection.
  • C. Incorrect – can occur but is not the defining infection.
  • D. Incorrect – a major HIV-associated infection but not the original AIDS-defining one.

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