Pathology · single question

Gingival enlargement is seen in all of the following EXCEPT:

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  1. Phenytoin therapy
  2. Drug-induced gingival hyperplasia
  3. Vitamin C deficiency (scurvy)
  4. Herpes gingivostomatitis
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Correct answer: D. Herpes gingivostomatitis

  • A. Phenytoin (Dilantin), along with cyclosporine and calcium channel blockers (nifedipine), is a classic cause of drug-induced gingival enlargement.
  • B. Drug-induced gingival hyperplasia is a well-established condition caused by specific medications.
  • C. Vitamin C deficiency (scurvy) causes enlarged, bleeding, edematous gingiva due to defective collagen synthesis.
  • D. Correct. Herpes gingivostomatitis causes painful vesicles and ulcers throughout the oral mucosa and gingiva, but does NOT cause TRUE gingival enlargement (hyperplasia). It causes erythema and acute inflammation, not fibrous overgrowth.

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