Periodontics · single question

Gingival enlargement is NOT typically associated with which of the following conditions?

  1. Herpetic gingivostomatitis
  2. Vitamin C deficiency (scurvy)
  3. Sarcoidosis
  4. Phenytoin (Dilantin) usage
Show answer and explanation

Correct answer: A. Herpetic gingivostomatitis

Gingival enlargement (overgrowth/hyperplasia) is associated with: phenytoin (drug-induced fibroblast proliferation), calcium channel blockers (nifedipine), cyclosporine, vitamin C deficiency/scurvy (edematous gingival swelling with spontaneous bleeding), sarcoidosis (granulomatous infiltration), leukemia (leukemic infiltration), and hereditary gingival fibromatosis. Herpetic gingivostomatitis (primary HSV-1 infection) causes acute gingival INFLAMMATION, erythema, and ULCERATION, but NOT true gingival enlargement or overgrowth. The gingiva appears swollen due to acute inflammation, but this is not the same as fibrous or granulomatous gingival enlargement.

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