Periodontics · single question
Gingival enlargement is NOT typically associated with which of the following conditions?
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Correct answer: A. Herpetic gingivostomatitis
Gingival enlargement (overgrowth/hyperplasia) is associated with: phenytoin (drug-induced fibroblast proliferation), calcium channel blockers (nifedipine), cyclosporine, vitamin C deficiency/scurvy (edematous gingival swelling with spontaneous bleeding), sarcoidosis (granulomatous infiltration), leukemia (leukemic infiltration), and hereditary gingival fibromatosis. Herpetic gingivostomatitis (primary HSV-1 infection) causes acute gingival INFLAMMATION, erythema, and ULCERATION, but NOT true gingival enlargement or overgrowth. The gingiva appears swollen due to acute inflammation, but this is not the same as fibrous or granulomatous gingival enlargement.