Periodontics · single question

Most appropriate antibiotic for treating necrotizing ulcerative gingivitis (NUG)?

  1. Metronidazole
  2. Amoxicillin
  3. Azithromycin
  4. Clindamycin
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Correct answer: A. Metronidazole

METRONIDAZOLE 250-500mg TID x 7 days = antibiotic of choice for NUG. NUG caused predominantly by anaerobic spirochetes (Treponema), Fusobacterium, Prevotella — all highly susceptible to metronidazole's free radical generation in anaerobic environments. Must combine with mechanical debridement.

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