Endodontics · single question
For infective endocarditis prophylaxis, what is the correct amoxicillin dose for a 20-kg child without a penicillin allergy?
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Correct answer: B. 1,000 mg amoxicillin
The AHA/ADA recommended dose of amoxicillin for IE prophylaxis in children is 50 mg/kg (maximum 2,000 mg), given orally 30-60 minutes before the dental procedure. For a 20-kg child: 50 mg/kg × 20 kg = 1,000 mg. Adult dose is 2,000 mg. For penicillin-allergic patients, alternatives include azithromycin 500 mg (adult) / 15 mg/kg (child), clindamycin 600 mg (adult) / 20 mg/kg (child), or cephalexin. Note: Clindamycin was removed from the IE prophylaxis guidelines in the 2021 AHA update due to Clostridioides difficile risk.